Protein Cycling Diet: 27

Summary

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Abstract

Chapter 27:
Summary of the book Protein Cycling Diet.

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Summary

  • Neurodegenerative diseases like AD and PD are characterized by protein aggregates and condensates.

  • The aggregates, or at least the proteins that eventually form the aggregates, may be responsible for the disease.

  • The aggregate proteins may accumulate because the usual protein recycling systems of the cell cannot handle them.

  • The aggregate proteins may induce newly made proteins of the same type to mis-fold as well and accelerate the disease progression.

  • Non-selective autophagy as occurs during periods of restriction may recycle the aggregate proteins.

  • Non-selective autophagy may be triggered by amino acid restriction alone.

  • Alternate day amino acid restriction may be sufficient to counter-act and reverse the accumulation at any point and indefinitely delay progression of neurodegenerative diseases.

  • Nutrients other than protein must remain adequate in the diet including vitamins, minerals and essential fatty acids and should be guaranteed by taking supplements.

  • Other foodstuffs such as curcumin and resveratrol may enhance the autophagy inducing effects of protein cycling.

  • Heart disease, diabetes and cancer are much greater risks than all neurodegenerative diseases combined and the risk increases as overweight increases so weight control is a first priority.

  • Protein cycling may reduce heart disease, diabetes and cancer by enhancing autophagy.

  • Protein cycling can be used to reduce weight as well though the alternate day calorie restriction diet works faster while still promoting autophagy.

A website for discussing this book has been opened at: http://proteincycling.blogspot.com

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